Airway submucosal glands from cystic fibrosis swine suffer from abnormal ion transport across the serous acini, collecting duct, and ciliated duct
X Luan, JS Tam, S Jagadeeshan… - … of Physiology-Lung …, 2020 - journals.physiology.org
… of the fluid produced by the individual submucosal glands … CFTR-dependent gland secretion,
triggered serous acini epithelia … Acinar origin of CFTR-dependent airway submucosal gland …
triggered serous acini epithelia … Acinar origin of CFTR-dependent airway submucosal gland …
Neuropeptide regulation of secretion and inflammation in human airway gland serous cells
DB McMahon, RM Carey, MA Kohanski… - … Respiratory Journal, 2020 - Eur Respiratory Soc
… Airway submucosal gland serous cells are sites of … defects in CFTR-dependent serous
secretion contribute to CF … Gland acini are likely significant contributors of cytokines [54]…
secretion contribute to CF … Gland acini are likely significant contributors of cytokines [54]…
Secretory cells dominate airway CFTR expression and function in human airway superficial epithelia
… in the regulation of airway epithelial Cl − and fluid secretory rates. … Airway submucosal
glands from cystic fibrosis swine suffer from abnormal ion transport across the serous acini…
glands from cystic fibrosis swine suffer from abnormal ion transport across the serous acini…
Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs
W Yu, TO Moninger, AL Thurman… - Proceedings of the …, 2022 - National Acad Sciences
… SMGs secrete liquid and most of the mucus in large airways; the … To better understand the
potential role of the two acinar cell types in electrolyte and liquid secretion, we also curated a …
potential role of the two acinar cell types in electrolyte and liquid secretion, we also curated a …
Early studies of airway submucosal glands
JH Widdicombe - … Journal of Physiology-Lung Cellular and …, 2019 - journals.physiology.org
… Acinar origin of CFTR-dependent airway submucosal gland fluid secretion. Am J Physiol
Lung Cell Mol Physiol 292: L304–L311, 2007. doi:10.1152/ajplung.00286.2006. …
Lung Cell Mol Physiol 292: L304–L311, 2007. doi:10.1152/ajplung.00286.2006. …
PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa
DB McMahon, RM Carey… - … of Physiology-Lung …, 2021 - journals.physiology.org
… of synergistic CFTR-dependent PAR-2/VIPR secretion may … structure of an airway submucosal
gland, showing cystic … at the distal acini, which have been demonstrated to be the origin of …
gland, showing cystic … at the distal acini, which have been demonstrated to be the origin of …
[HTML][HTML] CFTR-rich ionocytes mediate chloride absorption across airway epithelia
L Lei, S Traore, GSR Ibarra, PH Karp… - The Journal of …, 2023 - Am Soc Clin Investig
… -airway epithelia and submucosal glands, thus determining … absorption and CFTR-dependent
liquid secretion. Our … CFTR within the acinus and ducts of the airway epithelium could …
liquid secretion. Our … CFTR within the acinus and ducts of the airway epithelium could …
Inverse regulation of secretion and inflammation in human airway gland serous cells by neuropeptides upregulated in allergy and asthma
DB McMahon, MA Kohanski, CCL Tong… - bioRxiv, 2019 - biorxiv.org
… Airway submucosal gland serous cells are sites of expression … Defects in CFTR-dependent
serous cell secretion likely play … on secretion from primary human airway gland serous acinar …
serous cell secretion likely play … on secretion from primary human airway gland serous acinar …
Pendrin mediates bicarbonate secretion and enhances CFTR function in airway surface epithelia
… secretion by Calu-3 cells may be appropriate for submucosal gland acinar cells, since we
detected little pendrin in glands by … Supplementary Figure 2 CFTR-dependent intracellular …
detected little pendrin in glands by … Supplementary Figure 2 CFTR-dependent intracellular …
[HTML][HTML] Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium
D Angyal, TA Groeneweg, A Leung, M Desain… - Cellular & Molecular …, 2024 - Springer
… Background … activity of NFκB in acinar cells, which, together with the release of damage-associated …
CFTR-mediated fluid secretion in the submucosal glands of the respiratory tract, and …
CFTR-mediated fluid secretion in the submucosal glands of the respiratory tract, and …